The Correlation between Retinal Nerve Fibre Layer Thickness, Optic Nerve Head Parameter, and Related Risk Factor in Glaucoma Patient Oral Presentation - Observational Study - Resident
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Glaucoma, RNFL thickness, optical coherence tomography, optic nerve head
Abstract
Introduction & Objectives
To investigate the correlation between retinal nerve fibre layer (RNFL) thickness and the past RNFL
thickness, related risk factor (gender, age, myopia, intraocular pressure (IOP), blood pressure). And
RNFL parameter (symmetricity and four quadrants RNFL thickness) and optic nerve head parameter
(rim area and vertical cup disc ratio)
Methods
39 right eyes of both sex and various age underwent examination including IOP measurement,
subjective refraction for determining refractive error, and optical coherence tomography (OCT) for
RNFL and ONH analysis. The follow up were done after one year.
Results
The RNFL symmetricity, superior, nasal, inferior, temporal RNFL thickness showed significance
correlation with RNFL thickness (R= 0.487, p= 0.002), (R= 0.915, R= 0.749, R= 0.897, R= 0.702
with p= <0.001), but not showed significance correlation with rim area and vertical cup disc ratio
(R= 0.175, p= 0.286) and (R= -0.093, p= 0.574). A significance correlation also showed with
increasing age, gender, and systolic blood pressure (R= -0.387, p= 0.015), (R= 0.441, p= 0.005) and
(R= -0.418, p= 0.008). But not showed significance correlation with history of past RNFL thickness,
refractive error, IOP, and diastolic blood pressure (R= 0.258, p= 0.113), (R= 0.005, p= 0.975), (R=
-0.234, p=0.152), and (R= 0.060, p=0.717).
Conclusion
RNFL thickness measurements showed significance correlation with RNFL parameter. It is not clear
if past RNFL thickness, refractive error and IOP related with RNFL thickness even showed
significance correlation with age, gender, and systolic blood pressure.
Full text article
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Authors
Copyright (c) 2023 Arif Kusuma Wardhana, Retno Ekantini, Tatang Talka Gani, Krisna Dwi Purnomo Jati
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