Malignant Triton Tumor without Von Recklinghausen’s Neurofibromatosis in a 16 year-old Indonesian Girl: A Case Report
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malignant peripheral nerve sheath tumor, malignant triton tumor, s-100 protein
Abstract
Background: To diagnose malignant peripheral nerve sheath tumor with rhabdomyoblastic differentiation in malignant triton tumor which has a rare incidence.
Case Illustration: We reported a case in a 16 year-old girl who presented with progressively painless proptosis of the left eye and decreased visual acuity. There was no evidence of Recklinghausen’s disease. She underwent surgery and radiotherapy. The histopatologic findings showed malignant peripheral nerve sheath tumor (MPNST). Four years later, she suffered recurrence proptosis and decreased visual acuity. Histomorphology supported by immunostaining with S-100 protein confirmed the diagnosis of malignant triton tumor. She underwent chemotherapy and enucleation. Conclusion: This case highlights the prudent use of immunohistochemistry that is essential in making an early detection and a correct diagnosis.
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References
2. Mae K, Kato Y, Usui K, Abe N, Tsuboi R. A case of Malignant Peripheral Nerve Sheath Tumor with Rhabdomyoblastic Differentiation: Malignant Triton Tumor. Case Rep Dermatol 2013;5:373–378
3. McConell YJ, Giaucomantonio CA. Malignant Triton Tumors-complete surgical resection and adjuvant radiotherapy associated with improved survival. J. Surg. Oncol. 2012; 106:51–56.
4. Tripathy K e al. A Rare Malignant Triton Tumor. Case Rep Neurol 2010;2:69–73