Outcomes of GDD Implantation in NVG Patients at Cipto Mangunkusumo Hospital: A 3-Year Study
Abstract
Introduction: Neovascular glaucoma is a challenging type of glaucoma to manage, due to its progressive nature. Achieving good intraocular pressure (IOP) in neovascular glaucoma cases often requires the aid of filtering surgery, preferably with a glaucoma implant/drainage device. This study aims to evaluate the outcomes of glaucoma drainage device (GDD) implantation for neovascular glaucoma patients in Cipto Mangunkusumo Hospital.
Methods: A total of 77 eyes with neovascular glaucoma were included in this study, which underwent GDD implantation in Cipto Mangunkusumo Hospital between 2020 to 2022. Baseline data include age, gender, laterality, implant type used, underlying ocular condition, systemic comorbid, visual acuity (VA), IOP, and prescribed glaucoma medications. The postoperative VA and IOP were measured at 1 day, 1 week, 1 month, 3 months, 6 months, 1 year, and 18 months or above. Complications and additional surgical interventions were noted. Success criteria based on the IOP and amount of glaucoma medications were evaluated at least 6 months postoperatively.
Results: The mean IOP at baseline was 45.91 ± 13.9 mmHg with 3.42 ± 0.77 glaucoma medications. At 6 months postoperative, mean IOP was decreased to 13.84 ± 8.6 mmHg with 1.21 ± 1.18 glaucoma medications. At 6 months follow-up, 32.0% patients achieved complete success and 48.0% patients achieved qualified success. At 1 year postoperative, the Kaplan-Meier analysis for GDD success in neovascular glaucoma cases was estimated to be 79.2%.
Conclusion: GDD implantation is an effective surgical option in treating neovascular glaucoma cases.
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References
Havens SJ, Gulati V. Neovascular Glaucoma. Dev Ophthalmol. 2016; 55: 196—204. doi: 10.1159/000431196
Liao N, Li C, Jiang H, Fang A, Zhou S, Wang Q. Neovascular glaucoma: a retrospective review from a tertiary center in China. BMC Ophthalmol. 2016; 16: 14. https://doi.org/10.1186/s12886-016-0190-8
Rani PK, Sen P, Sahoo NK, Senthil S, Chakurkar R, Anup M, et al. Outcomes of neovascular glaucoma in eyes presenting with moderate to good visual potential. Int Ophthalmol. 2021; 41: 2359–68.
Urbonavičiūtė D, Buteikienė D, Janulevičienė I. A Review of Neovascular Glaucoma: Etiology, Pathogenesis, Diagnosis, and Treatment. Medicina. 2022; 58(12): 1870. https://doi.org/10.3390/medicina58121870
Rojananuangnit K, Jiaranaisilawong P, Rattanaphaithun O, Sathim W. Surgical Outcomes of Glaucoma Drainage Device Implantation in Refractory Glaucoma Patients in Thailand. Clin Ophthalmol. 2022; 16: 4163—78. doi: 10.2147/OPTH.S393730.
Dhingra D, Bhartiya S. Evaluating glaucoma surgeries in the MIGS context. Rom J Ophthalmol. 2020; 64(2): 85—95.
Iwasaki K, Kojima S, Wajima R, Okazaki T, Yokoyama Y, Inoue T, et al. Comparing Surgical Outcomes in Neovascular Glaucoma between Tube and Trabeculectomy: A Multicenter Study. Ophthalmology Glaucoma. 2022; 5(6): 672—80. https://doi.org/10.1016/j.ogla.2022.05.003
Malgi VS, Gawas L, Iyer AS, Rao A. Clinical profile and outcomes of neovascular glaucoma in the era of anti-vascular endothelial growth factor. Indian J Ophthalmol. 2021; 69(10): 2728—33. doi: 10.4103/ijo.IJO_528_21
Purtskhvanidze K, Saeger M, Treumer F, Roider J, Nölle B. Long-term results of glaucoma drainage device surgery. BMC Ophthalmol. 2019; 19(1): 14. doi: 10.1186/s12886-019-1027-z.
Noor NA, Mustafa S, Artini W. Glaucoma drainage device implantation with adjunctive intravitreal bevacizumab in neovascular glaucoma: 3-year experience. Clin Ophthalmol. 2017; 11: 1417—22. doi: 10.2147/OPTH.S137470.
Lin P, Zhao Q, He J, Fan W, He W, Lai M. Comparisons of the short-term effectiveness and safety of surgical treatment for neovascular glaucoma: a systematic review and network meta-analysis. BMJ Open. 2022; 12(5): e051794. doi: 10.1136/bmjopen-2021-051794.
Kung FF, Knier CG, Garmany A, Mejia CA, Sargent JM, Dogahe SJ, et al. Need for Additional Glaucoma Surgery and Complications Following Glaucoma Drainage Device Surgery. J Glaucoma. 2021; 30(6): 508—14. doi: 10.1097/IJG.0000000000001827.
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Copyright (c) 2025 Andrew John Widya Sieman, Virna Dwi Oktariana

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