Emerging Challenges of Acute Bilateral Diabetic Cataract in Pediatric: Insight to Early Detection and Management– A Case Report

Clara Valentina, MD (1) , I Wayan Eka Sutyawan, MD (2) , Ni Made Ayu Surasmiati, MD (3) , I Made Agus Kusumadjadja, MD (4) , I Wayan Gede Jayanegara (5)
(1) Udayana University Faculty of Medicine/RSUP Prof IGNG Ngoerah, Denpasar, Bali , Indonesia
(2) Udayana University Faculty of Medicine/RSUP Prof IGNG Ngoerah, Denpasar, Bali , Indonesia
(3) Udayana University Faculty of Medicine/RSUP Prof IGNG Ngoerah, Denpasar, Bali , Indonesia
(4) Udayana University Faculty of Medicine/RSUP Prof IGNG Ngoerah, Denpasar, Bali , Indonesia
(5) Udayana University Faculty of Medicine/RSUP Prof IGNG Ngoerah, Denpasar, Bali , Indonesia

Abstract

Purpose:


To report rare case of acute bilateral cataract in pediatric with Type 1 Diabetes Mellitus as ocular complication despite of good glycaemic controls and its management.


Methods:


A 17-year-old male patient complained of blurry vision and glare in both eyes(BE) since 3 months in newly diagnosed T1DM (HbA1c 10% --> now 6.3%). Visual Acuity (VA) was 6/45PH6/21f2, with correction S-1.50 advancing to 6/18 in BE. Slitlamp examination of BE revealed lens opacity (P3),central position, 3mm in diameter, retinometri 0.32. Posterior segment evaluation and intraocular pressure (IOP) were within normal limits. Right eye (RE) was underwent lensectomy and IOL insertion under GA.


Results: 


Postoperative RE with final VA of 6/18 PHNI and IOP of 43 mmHg. Patient was given antiinflammation eyedrops, oral and topical antiglaucoma, and received controlled final IOP of 8mmHg within 3 days and remain stable until now without antiglaucoma. Result was satisfying despite of uncomplicated secondary glaucoma as short-term complication that resolved with therapy. Evaluation and close monitoring postoperatively is needed and play significant role in visual outcome.


Conclusions:


Early detection for ocular complication in DM is needed as cataract genesis process still progressing despite of good glycaemic control. Ocular manifestation may present as early sign of undiagnosed T1DM or as its complications. Comprehensive and holistic multidicipline treatment, glycaemic control,  and routine evaluation is essential and play significant role in the success of metabolic cataract therapy and progression of microvascular complications due to DM. Lensectomy + IOL implantation still the mainstay therapy in pediatric cataract.  Awareness play vital role as it possibly cause decreased vision and or amblyopia, leading to blindness.


 

Full text article

Generated from XML file

References

1. Craig ME, Jefferies C, Dabelea D, Balde N, Seth A, Donaghue KC. Definition, epidemiology, and classification of diabetes in children and adolescents. Pediatric Diabetes. 2014 Sep;15(S20):4–17

2. Sayin N. Ocular complications of diabetes mellitus. World Journal of Diabetes. 2015;6(1):92.

3. Geloneck MM, Forbes BJ, Shaffer J, Ying G, Binenbaum G. Ocular Complications in Children with Diabetes Mellitus. Ophthalmology. 2015 Dec;122(12):2457–64

4. M. Edward Wilson, Levin AV, Trivedi RH, Kruger SJ, Elliott LA, Ainsworth JR, et al. Cataract associated with type-1 diabetes mellitus in the pediatric population. Journal of American Association for Pediatric Ophthalmology and Strabismus. 2007 Apr 1;11(2):162–5

5. Tsai L. 2021-2022 basic and clinical science course. Section 11, Lens and cataract. San Francisco: American Academy Of Ophthalmology; 2021.

6. Šimunović M, Paradžik M, Škrabić R, Unić I, Bućan K, Škrabić V. Cataract as Early Ocular Complication in Children and Adolescents with Type 1 Diabetes Mellitus. International Journal of Endocrinology. 2018;2018:1–6.

7. Costagliola C, Dell’Omo R, Prisco F, Iafusco D, Landolfo F, Parmeggiani F. Bilateral isolated acute cataracts in three newly diagnosed insulin dependent diabetes mellitus young patients. Diabetes Research and Clinical Practice. 2007 May;76(2):313–5.

8. Iafusco D, Prisco F, Romano MR, Dell’Omo R, Libondi T, Costagliola C. Acute juvenile cataract in newly diagnosed type 1 diabetic patients: a description of six cases. Pediatric Diabetes. 2011 Apr 7;12(7):642–8.

9. Quintos JB, Torga AP, Simon MA. Diabetes cataract in a 10-year-old girl with new-onset type 1 diabetes mellitus. BMJ Case Reports. 2019 Jan;12(1):e227437.

10. Donaghue KC, Wadwa RP, Dimeglio LA, Wong TY, Chiarelli F, Marcovecchio ML, et al. Microvascular and macrovascular complications in children and adolescents. Pediatric Diabetes. 2014 Sep;15(S20):257–69.

11. Couper JJ, Haller MJ, Ziegler AG, Knip M, Ludvigsson J, Craig ME. Phases of type 1 diabetes in children and adolescents. Pediatric Diabetes. 2014 Sep;15(S20):18–25.

12. Children and Adolescents. Diabetes Care. 2014 Dec 23;38(Supplement_1):S70–6.https://doi.org/10.2337/dc15-S014

13. Veselin Skrabic, Ivanisevic M, Stanic R, Unic I, Kajo Bucan, Davor Galetovic. Acute Bilateral Cataract With Phacomorphic Glaucoma in a Girl With Newly Diagnosed Type 1 Diabetes Mellitus. Journal of pediatric ophthalmology and strabismus. 2010 Jan 1;47(1):1–3

14. Papadimitriou DT, Bothou C, Filippos Skarmoutsos, Vassiliki Papaevangelou, Papadimitriou A. Acute Bilateral Cataract in Type 1 Diabetes Mellitus. Annals of pediatrics & child health. 2015 Jan 1;3(7).

doi: 10.6084/m9.figshare.13251911.v1. Epub 2015 Oct 2. PMID: 34414256; PMCID: PMC8373202.

15. Nischal KK, Medsinge A. Pediatric cataract: challenges and future directions. Clinical Ophthalmology. 2015 Jan;77.

16. Hered RW. 2022-2023 BASIC AND CLINICAL SCIENCE COURSE, SECTION 06 : pediatric ophthalmology and... strabismus print. S.L.: Amer Academy Of Ophthalmo; 2022.

17. Chen D, Gong X, Xie H, Zhu X, Li J, Zhao Y. The long-term anterior segment configuration after pediatric cataract surgery and the association with secondary glaucoma. Scientific Reports. 2017 Feb 21;7(1).

18. Gasper C, Trivedi RH, Wilson ME. Complications of Pediatric Cataract Surgery. Pediatric Cataract [Internet]. 2016 [cited 2022 Feb 15];57:69–84.

19. Ventura MC, Sampaio VV, Ventura BV, Ventura LO, Nosé W. Congenital cataract surgery with intraocular lens implantation in microphthalmic eyes: visual outcomes and complications. Arquivos Brasileiros de Oftalmologia. 2013 Aug;76(4):240–3.https://doi.org/10.1590/s0004-27492013000400011

20. Whitman MC, Vanderveen DK. Complications of Pediatric Cataract Surgery. Seminars in Ophthalmology. 2014 Sep 1;29(5-6):414–20.

https://doi.org/10.3109/08820538.2014.959192

Authors

Clara Valentina, MD
claraval94@gmail.com (Primary Contact)
I Wayan Eka Sutyawan, MD
Ni Made Ayu Surasmiati, MD
I Made Agus Kusumadjadja, MD
I Wayan Gede Jayanegara
Valentina, C., Sutyawan, I. W. E., Surasmiati, N. M. A., Kusumadjadja, I. M. A., & I Wayan Gede Jayanegara. (2025). Emerging Challenges of Acute Bilateral Diabetic Cataract in Pediatric: Insight to Early Detection and Management– A Case Report. Ophthalmologica Indonesiana, 51(2), 39-49. https://doi.org/10.35749/journal.v51i2.101671

Article Details

How to Cite

Valentina, C., Sutyawan, I. W. E., Surasmiati, N. M. A., Kusumadjadja, I. M. A., & I Wayan Gede Jayanegara. (2025). Emerging Challenges of Acute Bilateral Diabetic Cataract in Pediatric: Insight to Early Detection and Management– A Case Report. Ophthalmologica Indonesiana, 51(2), 39-49. https://doi.org/10.35749/journal.v51i2.101671