CORRELATION OF CENTRAL CORNEAL THICKNESS TO ACTUAL INTRAOCULAR PRESSURE IN MYOPIA PATIENTS

Hadwer Wicaksono Pandjaitan (1) , Andrini Ariesti (2)
(1) a:1:{s:2:"en";s:23:"RSUP DR M Djamil Padang";} , Indonesia
(2) RSUP DR M Djamil Padang , Indonesia

Abstract

Background : Central Corneal Thickness (CCT) is promote in the diagnosis and management of glaucoma, especially in myopic patients. Understanding the correlation between CCT and IOP (Intraocular Pressure) aids in glaucoma detection and control. The objective of this study is to determine the correlation between CCT and actual IOP in myopic patients.


Methods : This research is an observational study with ethical committee approval, involving medical students from the Faculty of Medicine at Andalas University undergoing clinical clerkships at Dr. M Djamil Padang General Hospital. They were grouped into emmetropia, mild myopia, and moderate myopia. Data included visual acuity measurements, autorefraction, CCT measurements using OCT, and IOP with CCT correction. Samples with eye abnormalities, systemic conditions, myopia > 6D, a history of eye surgery, contact lens wear, and IOP > 21 mmHg were excluded. All data were analyzed statistically.


Results : The study involved 78 eyes from 78 individuals, consisting of 26 eyes per group. The actual CCT and IOP values in mild myopia, moderate myopia and emmetropia are 506.31 ± 11,263 μm with 15.81 ± 1,234 mmHg, 533.96 ± 21,342 μm with 16.12 ± 1,336 mmHg, and 487.81 ± 28,272 μm with 15.35 ± 1.056 mmHg. There was a strong positive correlation between CCT and IOP (r=0.737, p=0.000), as well as a moderate negative correlation between CCT and actual IOP (r=-0.492, p=0.000).


Conclusion : This research reveals a negative correlation between CCT and actual IOP in myopic patients, highlighting the importance of glaucoma screening for myopic patients due to their thinner corneas.

Full text article

Generated from XML file

References

Tan NYQ, et al. Glaucoma in myopia: diagnostic dilemmas. Br J Ophthalmol 2019; pp :1–9.

World Health Organization. World Report of Vision. Geneva, Switzerland: WHO. 2019. pp 1-180

Allison K, Patel D, Alabi O. Epidemiology of Glaucoma: the Past, Present, and Predictions for the Future. Cureus 12(11). 2020; pp. 1-9.

Garcia M, Medina M, et al. Central corneal thickness, intraocular pressure and degree of myopia in adult myopic population aged 20 to 40 years in Southeast Spain: determination and relationships. Clin Ophthalmol. 2011; pp. 249-258.

Maiciulaitiene R, Januleviciene I. Correlation Between Structure and Function in Glaucomatous Damage. Biophysical Properties in Glauc`oma. Switzerland: Springer, 2019: pp 145-9

Qiu K, Lu X, Zhang R, Wang G. Relationship of corneal hysteresis and optic nerve parameters in healthy myopic subjects. Scientific reports. 2017. 7:17538

Carbonaro F, Hysi PG, Fahy SJ, et al. Optic disc planimetry, corneal hysteresis, central corneal thickness, and intraocular pressure as risk factors for glaucoma. Am J Ophthalmol. 2014 Feb;157(2):441-6.

Gordon MO, Kass MA.What We Have Learned From the Ocular Hypertension Treatment Study. American Journal of Ophthalmology, 189, xxiv–xxvii. 2018.

Rapuano CJ, Stout JT, McCannel CA. Aqueous humor, iris, and ciliary body. In: Fundamental and principles of ophthalmology. San Francisco: American Academy of Ophthalmology. 2022-2023. pp. 269-279.

Lee AJ, et al. Intraocular pressure associations with refractive error and axial length in children. Br J Ophthalmol 2004;88:5–7

Choi JA, et al. Age-Related Association of Refractive Error with Intraocular Pressure in the Korea National Health and Nutrition Examination Survey. PLOS ONE 2014, 9(11): e111879. doi:10.1371/journal.pone.0111879

Medina MG, et al. Central corneal thickness, intraocular pressure, and degree of myopia in an adult myopic population aged 20 to 40 years in southeast Spain: determination and relationships. Dove Press Journal, Clinical Ophthalmology 2011:5 249–258

Priyadarshini TA. Correlation Between Central Corneal Thickness (CCT) and Retinal Nerve Fiber Layer (RNFL). Disertation. The Tamilnadu DR MGR Medical University. Chennai. 2013

Sng CCA, Ang M, Barton K. Central corneal thickness in glaucoma. Curr Opin Ophthalmol 2017, 28:120–126 DOI:10.1097/ICU.0000000000000335

Authors

Hadwer Wicaksono Pandjaitan
hadwerpandjaitan@gmail.com (Primary Contact)
Andrini Ariesti
Author Biography

Andrini Ariesti, RSUP DR M Djamil Padang

-

Pandjaitan, H. W., & Ariesti, A. . (2025). CORRELATION OF CENTRAL CORNEAL THICKNESS TO ACTUAL INTRAOCULAR PRESSURE IN MYOPIA PATIENTS. Ophthalmologica Indonesiana, 51(1). https://doi.org/10.35749/journal.v51i1.101669

Article Details

How to Cite

Pandjaitan, H. W., & Ariesti, A. . (2025). CORRELATION OF CENTRAL CORNEAL THICKNESS TO ACTUAL INTRAOCULAR PRESSURE IN MYOPIA PATIENTS. Ophthalmologica Indonesiana, 51(1). https://doi.org/10.35749/journal.v51i1.101669
No Related Submission Found