Bevacizumab vs Ranibizumab in Macular Edema due to Retinal Vein Occlusion: Short-term Outcomes
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vein occlusion, macular edema, macular thickness, visual acuity
Abstract
Introduction & Objectives
Bevacizumab or Ranibizumab was widely used as therapy for macular edema (ME) in retinal vein
occlusion (RVO) and diabetic retinopathy. The purpose of this study was to comparing short-term
outcomes for patients who received intravitreal Bevacizumab (IVB) injection or Ranibizumab (IVR)
for ME due to RVO
Methods
This was observational, cross sectional study comparing patients received IVB or IVR. Primary
outcomes data (visual acuity and central macular thickness/CMT) and secondary outcomes data
(number injection and intra ocular pressure/IOP) were collected at baseline and 3 months after
injection
Results
There were 4 eyes in each group. There were no significant difference in mean change of visual
acuity (-0.275±0.25 vs -0.15±0.5 logMAR; p=0.676) and CMT (-171.50±129.08 vs -98.25±37.67 um;
p=0.345) in IVB vs IVR groups. There were also no significant difference in mean change of IOP
(2±2.16 vs 2±4.69 mmHg; p=1) and number of injection (2.25±0.50 vs 1.75±0.9; p=0.401 ) in both
groups.
Conclusion
In short-term both IVB and IVB have relative similar outcomes on increasing visual acuity and
decreasing CMT in ME due to RVO
Full text article
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