The Role of Tumor Necrosis Factor (TNF) Alpha with Visual Field Defects in Primary Open Angle Glaucoma (POAG) Oral Presentation - Observational Study - Resident

Muhammad Hendy Hasudungan Hutabarat (1) , Masitha Dewi Sari (2)
(1) , Indonesia
(2) , Indonesia

Abstract

Introduction & Objectives
Glaucoma is a group of progressive optic neuropathy disease characterized by degeneration of
retinal ganglion cells. This causes changes in the optic nerve and loss of visual field. Several studies
have revealed that there is a role for TNF Alpha in glaucoma cases. To determine the role Tumor
Necrosis Factor (TNF) Alpha Levels between visual field defects in Primary Open-angle Glaucoma
patients.



Methods
This study is Observational Analytical with cross sectional data collection method. Examination of
the field of view using the Humphrey visual field perimetry.



Results
The sample of this research was 30 people with 16 (53.3%) male and 14 people (46.7%) female.
Using the Spearman correlation test, it showed that there was no significant correlation between
TNF alpha and field of view (p = 0.119).



Conclusion
TNF Alpha level was not significantly related to visual field defects.

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References

Shields MB, Allingham RR, Damji KF, Freedman S, Moroi SE, Shafranov G. Shields' Textbook of Glaucoma. 6th Edition. Lippincott Williams and Wilkins.; 2011. pp. 176-85

Stamper RL, Lieberman MF, Drake MV. Primary Open Angle Glaucoma. In: Becker-Shaffer's Diagnosis and Therapy of the Glaucoma. 7th Edition. Elsevier Inc.; 2009. pp. 239-65

Weinreb RN, Aung T., Medeiros FA. The Pathophysiology and Treatment of Glaucoma. Journal of the American Medical Association. 2014 May 14;311(18): 1901-11

Khouri AS., Fechtner RD. Primary Open Angle Glaucoma. In: Glaucoma. 2nd Edition. Elsevier Inc.; 2015. pp 333-45

Joos KM., Kuchtey RW. Primary Open Angle Glaucoma. In: Albert And Jakobiec's Principles and Practice of Ophthalmology. 3rd Edition. Elsevier Inc.; 2008. pp 2543-47

Bowling B. Glaucoma. In: Kanski's Clinical Ophthalmology. 8th edition. Elsevier Inc.; 2016. pp 305-94

Cantor LB, Rapuano CJ, Cioffi GA. Basic and clinical science course: Glaucoma. Section 10. San Francisco: American Academy of Ophthalmology; 2016. pp 72-82

Kondhkar et al. Association of increased levels of plasma tumor necrosis factor alpha with primary open-angle glaucoma. 2018. Clinical Ophthalmology. Saudi Arabia.

Wong et all. T-Helper1/T-Helper2 Cytokine Imbalance in the Iris of Patients with Glaucoma. 2015. PlosOne. China.

Ghanem et all. Tumor Necrosis Factor Alpha and Interleukin-6 Levels in Patients with Primary Open-Angle Glaucoma. 2011. Journal of Clinical & Experimental Ophthalmology. Egypt.

Zhang et al. Prevalence of primary open angle glaucoma in the last 20 years: a metaanalysis and systematic reviews. 2021. Scientific Reports.

Authors

Muhammad Hendy Hasudungan Hutabarat
Masitha Dewi Sari
Hutabarat, M. H. H. ., & Sari, M. D. . (2024). The Role of Tumor Necrosis Factor (TNF) Alpha with Visual Field Defects in Primary Open Angle Glaucoma (POAG): Oral Presentation - Observational Study - Resident. Ophthalmologica Indonesiana, 49(S2). https://doi.org/10.35749/19xr0h91

Article Details

How to Cite

Hutabarat, M. H. H. ., & Sari, M. D. . (2024). The Role of Tumor Necrosis Factor (TNF) Alpha with Visual Field Defects in Primary Open Angle Glaucoma (POAG): Oral Presentation - Observational Study - Resident. Ophthalmologica Indonesiana, 49(S2). https://doi.org/10.35749/19xr0h91

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