COMPARISON OF ANGLE OPENING DISTANCE AND TRABECULAR IRIS SPACE AREA BEFORE AND AFTER LASER PERIPHERAL IRIDOTOMY IN ANGLE CLOSURE DISEASE Oral Presentation - Observational Study - Resident
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Angle-closure disease, LPI, SD AS-OCT
Abstract
Introduction & Objectives
Laser peripheral iridotomy (LPI) is the standard first-line therapy in angle closure disease to
increase anterior chamber angle width. Spectral Domain Anterior Segment Optical Coherence
Tomography (SD AS-OCT) is an instrument that has a quantitative parameter to measure anterior
chamber angle. Angle opening distance (AOD) and trabecular iris space area (TISA) are quantitative
parameters in SD AS-OCT. The purpose of this study is to compare AOD and TISA before and one
week after LPI in angle closure disease.
Methods
This is an analytical prospective study with a cross-sectional study design. Twenty-two eyes with
angle closure disease that met inclusion and exclusion criteria underwent LPI and SD AS-OCT before
and one week after LPI. Analysis was performed using SD AS-OCT parameters, such as AOD
(AOD500, AOD750) and TISA (TISA500, TISA750) in the temporal, nasal quadrants, and average.
Results
Twenty-two eyes with angle closure are divided into nine eyes with primary angle closure suspect,
seven eyes with primary angle closure, and six eyes with primary angle closure glaucoma. The mean
age of participants was 57.86±7.63 years. There was a significant increase in AOD500, AOD750,
TISA500, and TISA750 in the temporal and nasal quadrants, as well as in the average (P=0.0001)
based on a paired t test or Wilcoxon as an alternative. Average AOD750 had the highest T-value (T=
6.329) with a mean 0.20±0.096 before LPI and 0.31±0.144 one week after LPI.
Conclusion
There was a significant increase in AOD and TISA after one week LPI in angle closure disease.
Full text article
References
American Academy of Opthalmology. Section 10: Glaucoma. Basic and clinical science course. Edisi. San Francisco: American Academy of Ophthalmology; 2020. h. Hal 313.
Xu BY, Friedman DS, Foster PJ, Jiang Y, Pardeshi AA, Jiang Y, et al. Anatomic Changes and Predictors of Angle Widening after Laser Peripheral Iridotomy: The Zhongshan Angle Closure Prevention Trial. Ophthalmology. 2021 2021/08/01/;128(8):1161-8.
Tun TA, Baskaran M, Tan SS, Perera SA, Aung T, Husain R. Evaluation of the anterior segment angle-to-angle scan of cirrus highdefinition optical coherence tomography and comparison with gonioscopy and with the visante OCT. Journal Investigative Ophthalmology Visual Science. 2017;58(1):5964.
Han S, Sung KR, Lee KS, Hong JW. Outcomes of laser peripheral iridotomy in angle closure subgroups according to anterior segment optical coherence tomography parameters. Journal Investigative Ophthalmology Visual Science. 2014;55(10):6795-801.
Radhakrishnan S, Chen PP, Junk AK, NouriMahdavi K, Chen TC. Laser peripheral iridotomy in primary angle closure: a report by the American Academy of Ophthalmology. Journal Ophthalmology. 2018;125(7):1110-20.
Kansara S, Blieden LS, Chuang AZ, Baker LA, Bell NP, Mankiewicz KA, et al. Effect of laser peripheral iridotomy on anterior chamber angle anatomy in primary angle closure spectrum eyes. Journal of glaucoma. 2016;25(5):e469e74.
Zebardast N, Kavitha S, Krishnamurthy P, Friedman DS, Nongpiur ME, Aung T, et al. Changes in anterior segment morphology and predictors of angle widening after laser iridotomy in South Indian eyes. Journal Ophthalmology. 2016;123(12):2519-26.
Riva I, Micheletti E, Oddone F, Bruttini C, Montescani S, De Angelis G, et al. Anterior Chamber Angle Assessment Techniques: A Review. Journal of Clinical Medicine. 2020;9(12):3814.
Dai Y, Zhang S, Shen M, Zhou Y, Wang M, Ye J, et al. Modeling of gonioscopic anterior chamber angle grades based on anterior segment optical coherence tomography. Journal of Eye and Vision. 2020;7(1):30.
Jiang Y, Chang DS, Zhu H, Khawaja AP, Aung T, Huang S, et al. Longitudinal changes of angle configuration in primary angle-closure suspects: the Zhongshan Angle-Closure Prevention Trial. Journal Ophthalmology. 2014;121(9):1699-705.
Lee RY, Kasuga T, Cui QN, Huang G, He M, Lin SC. Association between baseline angle width and induced angle opening following prophylactic laser peripheral iridotomy. J Investigative Ophthalmology Visual Science. 2013;54(5):3763-70.
Tun TA, Sawicki A, Wilkos-Kuc A, Aung T, Zarnowski T. Circumferential Assessment of Changes in Anterior Segment Characteristics and Baseline Predictors of Angle Widening After Laser Iridotomy in Caucasian Eyes. Journal of Glaucoma. 2021;30(9):839-45.
Kim YK, Park KH. Laser Peripheral Iridotomy. Primary Angle Closure Glaucoma (PACG). Edisi: Springer; 2021. h. 45-56.
Koh V, Keshtkaran MR, Hernstadt D, Aquino MCD, Chew PT, Sng C. Predicting the outcome of laser peripheral iridotomy for primary angle closure suspect eyes using anterior segment optical coherence tomography. J Acta ophthalmologica. 2019;97(1):e57-e63.
Meduri E, Gillmann K, Bravetti GE, Niegowski LJ, Mermoud A, Weinreb RN, et al. Iridocorneal angle assessment after laser iridotomy with swept-source optical coherence tomography. Journal of Glaucoma.
Authors
Copyright (c) 2023 Rizki Fasa Ramdhani, R. Maula Rifada, Irawati Irfani, Elsa Gustianty, Sonie Umbara
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