Extensive Primary Orbital Malignant Melanoma Associated with Nevus of Ota
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primary orbital malignant melanoma, ota nevus
Abstract
Primary orbital malignant melanoma is an extremely rare condition to present alone without previous extension of choroidal or conjunctival involvement. We reported the first case of malignant orbital melanoma without ocular involvement in a patient with nevus of Ota. A 52-year-old man presented with left proptosis and extensive bluish black pigmentation on left side of the face classified as Tanino type II of nevus of Ota and left ocular melanocytosis from birth. CT scan imaging showed extensive orbital mass occupying most of the orbital space. Transconjunctival biopsy was performed and a very pigmented mass was discovered, confirming the histopathology result of malignant melanoma. The patient was given up to five cycles of chemotherapy regimen. On serial orbital CT Scan, 33% of the tumor mass has disappeared after completing three cycles.
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References
Henry HL, Chan MB, Kono T. Nevus of Ota: Clinical aspects and management. Skin Med 2003;2:89-96.
Sharon S, Grigg JR, Billson FA. Bilateral naevus of Ota with choroidal melanoma and diffuse retinal pigmentation in a dark
skinned person. Br J Ophthalmol 2005;89:1529.
John H, Britto JA. Nonchoroidal intraorbital malignant melanoma arising from naevus of Ota. Ophthal Plast Reconstr Surg 2010;63:387-9.
Radhadevi CV , Charles KS, Lathika VK. Orbital malignant melanoma associated withnevus of Ota. Indian J Ophthalmol
;61(6):306-10.
Albert DM, Miller JW, Jakobiec FA. Albert
& Jakobiec’s Principles & Practice of Oph- thalmology. 3rd ed., vol. 4. Philadelphia: WB Saunders & Co.; 2000. p. 3238-9.
Buntinx-Krieg T, Ouyang J, Cartwright M. An orbital malignant melanoma arising in cellular blue nevus in a patient with nevus of Ota. Cureus 2016;8(7).
Nitta K, Kashima T, Mayuzumi H, Akiyama H, Miyanaga T, Hirato J, Kishi S. Animal- type malignant melanoma associated with nevus of Ota in the orbit of a Japanese woman: a case report. Melanoma research 2014;24(3): 286.
Huang WH, Wang HW, Sun QN, Jin HZ, Liu YH, Zuo YG, Zhao YL. A new classifica- tion of nevus of Ota. Chinese medical journal 2013;126(20):3910-3914.
Figueira E, Rajak S, McKelvie P, Kalantzis, G, Ismail A, Gonzales M, Selva D. Primary orbital melanoma: a case series and literature review. Orbit 2018;37(5):352-357.
Guledgud MV, Patil K, Srivathsa SH, Malleshi SN. Report of rare palatal expression of Nevus of Ota with amendment of Tanino's classification. Indian Journal of Dental Research 2011;22(6):850.
Koranyi K, Slowik F, Hajda M, Banfalvi T. Primary orbital melanoma associated with oculodermal melanocytosis. Orbit. 2000;19;21-30
Agarwal P, Patel BC. Nevus Of Ota And Ito. StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2020. Available from: https://www.ncbi.nlm.nih.gov/books/NBK5 60574/
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